All tools

Predict ADMET (Absorption, Distribution, Metabolism, Excretion, Toxicity) properties from SMILES strings using machine learning models trained on Therapeutics Data Commons datasets.

Analyze amino acid composition and frequency in protein sequences

Predict protein secondary structure using the classic Chou-Fasman algorithm based on amino acid propensities

Apply various mutations to DNA sequences and visualize the changes. Generate point mutations, insertions, deletions, and substitutions with customizable rates.

Translate DNA sequences to protein sequences using genetic code

Convert FASTQ sequence files to FASTA format

Calculate GC content and nucleotide composition of DNA/RNA sequences. Analyze individual sequences or get combined statistics.

Convert GenBank files to FASTA format

Assess drug-likeness using Lipinski's rule of 5 criteria for oral bioavailability

Calculate comprehensive molecular properties and descriptors including molecular weight, LogP, TPSA, aromatic properties, and drug-likeness scores

Convert single-letter amino acid codes to three-letter codes

Fix problems in Protein Data Bank files for molecular simulation preparation

Convert Protein Data Bank files to Crystallographic Information File format

Convert Protein Data Bank files to FASTA sequence format

Convert Protein Data Bank files to MOL2 molecular format

Convert Protein Data Bank files to Structure Data Format

Visualize and analyze protein structures in 3D using Mol* (molstar), the same viewer used by AlphaFold DB and RCSB PDB

Calculate protein parameters, including molecular weight, theoretical pI, extinction coefficient, and severla indeces, including instability, aliphatic index, and GRAVY.

Predict protein stability based on physicochemical properties, hydrophobicity, charge distribution, and secondary structure propensities

Reverse translate protein sequences to possible DNA sequences

Quantitative estimate for protein-protein interaction inhibitor potential. Evaluates drug-likeness for compounds targeting PPIs.

Generate random DNA sequences with customizable length, GC content, and restriction sites for molecular cloning and testing purposes.

Generate random protein sequences with customizable length, composition, and amino acid properties

Generate random RNA sequences with customizable types and structural features

Generate reverse, complement, or reverse-complement of DNA/RNA sequences

Convert Structure Data Format files to Protein Data Bank format

Convert three-letter amino acid codes to single-letter codes

Screen compounds for structural toxicity alerts using PAINS, Brenk filters, and custom toxicity patterns

Convert plain text sequence files to FASTA format