Fetch UniProt protein sequence files, JSON records, and available sequence content by accession. Learn more
Fetch UniProt protein sequence files, JSON records, and available sequence content by accession. Learn more
Fetch UniProt protein sequence files, JSON records, and available sequence content by accession. Learn more
Download PDB, CIF, and FASTA files from RCSB PDB by 4-character structure ID.
Download AlphaFold DB predicted structures and confidence files by UniProt accession.
Download BindingDB binding record files by BindingDB monomer ID.
Download InterPro protein family and domain records as JSON by InterPro ID.
Download PDBe structure files as PDB and CIF by PDB ID.
Download QuickGO Gene Ontology term records as JSON by GO ID.
Analyze amino acid composition of protein sequences. The tool accepts FASTA sequences and outputs the percentage of each amino acid in the sequence.
Scan protein sequences for biologically important motifs including glycosylation sites, phosphorylation sites, nuclear localization signals, prenylation motifs, and more.
Number antibody and T cell receptor variable domain sequences using IMGT, Chothia, Kabat, Martin, AHo, or Wolfguy. Reports chain type, the best HMM species match, and optional germline assignments.
Download ChEBI chemical entity records as JSON by ChEBI ID.
Download PDB, CIF, and FASTA files from RCSB PDB by 4-character structure ID.
Download AlphaFold DB predicted structures and confidence files by UniProt accession.
Download BindingDB binding record files by BindingDB monomer ID.
Download InterPro protein family and domain records as JSON by InterPro ID.
Download PDBe structure files as PDB and CIF by PDB ID.
Download QuickGO Gene Ontology term records as JSON by GO ID.
Analyze amino acid composition of protein sequences. The tool accepts FASTA sequences and outputs the percentage of each amino acid in the sequence.
Scan protein sequences for biologically important motifs including glycosylation sites, phosphorylation sites, nuclear localization signals, prenylation motifs, and more.
Number antibody and T cell receptor variable domain sequences using IMGT, Chothia, Kabat, Martin, AHo, or Wolfguy. Reports chain type, the best HMM species match, and optional germline assignments.
Download ChEBI chemical entity records as JSON by ChEBI ID.
Configure inputs to begin
Set options on the left, then click “Fetch downloads” — or start from an example.
P00533
P69905
Q8W3K0
UniProt Download fetches protein sequence files and JSON records from UniProt using a UniProt accession. It returns FASTA and JSON downloads, optional CIF structure links from cross-references, plus inline sequence content when the record includes a sequence.
Use this tool when you need a clean protein FASTA file for alignment, sequence analysis, structure prediction, or record keeping.
| Input | Description |
|---|---|
Entry ID | UniProt accession. Examples: P00533, P69905, Q8W3K0. |
| Setting | Description |
|---|---|
Database | Opens the selected database download tool. |
Output format | Return all files, FASTA, JSON, or CIF. |
| File | Format | Use |
|---|---|---|
| FASTA | .fasta | Protein sequence record for analysis tools. |
| JSON | .json | UniProtKB record with identifiers, annotation, and metadata. |
| CIF | .cif | Structure file link when the UniProt record includes a mapped structure. |
| Protein sequence | .fasta | Inline FASTA generated from sequence content when available. |
The FASTA output is ready for sequence tools such as Protein Parameters, Amino Acid Composition, Clustal Omega, and ESMFold.
Filenames follow the pattern:
uniprot-P00533-fasta.fasta
uniprot-P00533-json.json
uniprot-P00533-1m17.cif
uniprot-P00533-protein-sequence.fastaThe Details tab summarizes the accession, record title, file label, format, source type, filename, and URL.
Use the accession for direct downloads. Gene names can refer to multiple proteins, isoforms, or organisms, so they are better suited to database search first.
The provider can retrieve UniProtKB records by accession. The record metadata indicates whether the entry is reviewed or unreviewed when that information is available.
Yes. The FASTA file can be used with structure prediction tools such as ESMFold, AlphaFold2, and Boltz-2.