Predict properties before you synthesize
Calculate molecular weight, isoelectric point, extinction coefficient, stability indices, and hydrophobicity—all from sequence alone.
Protein Parameters
All-in-one property calculator: MW, pI, extinction coefficient, amino acid composition, and more.
NetSolP
Deep learning solubility prediction. Assess if your protein will express solubly in E. coli.
Instability Index
Predict protein stability in vitro. Scores >40 indicate potentially unstable proteins.
Hydrophobicity Plot
Visualize hydropathy profiles along the sequence. Identify transmembrane regions and surface residues.
Isoelectric Point
Predict pI for purification planning. Essential for IEF, ion exchange, and buffer selection.
GRAVY
Grand average of hydropathicity. Assess overall protein hydrophobicity for solubility prediction.
Why researchers choose ProteinIQ
Get all key properties in one analysis with batch support
Running multiple property calculators is tedious and error-prone
Predict stability and solubility indices before ordering
Ordering synthesis before knowing if protein will express well
Automatic extinction coefficient with absorbance guidelines
Manual concentration calculations from extinction coefficients
Analyze multiple sequences and compare side-by-side
No easy way to compare properties across variants
How it works
Comprehensive protein property prediction from amino acid sequences. Calculate biophysical parameters essential for expression, purification, and experimental design without synthesizing a single protein.
Input sequences
Paste or upload protein sequences in FASTA
Calculate properties
Compute MW, pI, extinction coefficient, and more
Analyze stability
Assess instability index and aliphatic index
Visualize hydrophobicity
Plot hydropathy profiles along the sequence
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