Antibody engineering workflows

Engineer antibody candidates with evidence at every step

Number variable regions, review humanness and developability, predict structures, model antibody-antigen complexes, and keep every output tied to the sequence it supports.

proteiniq.io/app/workflows/templates?template=antibody-humanization-review

Built for antibody engineering

Antibody campaigns often move between sequence annotation, germline context, humanness review, developability screening, structure prediction, binding-site inspection, and complex modeling. The hard part is keeping those outputs comparable without turning every question into a local tooling project.

Faithful upstream wrappers

ProteinIQ wraps antibody tools without replacing their scoring, numbering, defaults, or output conventions with hidden local logic.

Sequence and structure continuity

Heavy chains, light chains, tables, modeled structures, and downstream complex outputs stay connected across workflow steps.

Built for review, not black boxes

The page organizes annotation, triage, modeling, docking, and design outputs so scientists can inspect the evidence behind a candidate.

Realistic antibody engineering scope

ProteinIQ helps prioritize and organize computational evidence; experimental binding, expression, immunogenicity, and developability assays remain essential.

Heavy-chain, light-chain, paired, nanobody, and repertoire-style inputs need different preparation and interpretation rules.

Numbering, germline calls, liability screens, language-model outputs, structures, and docking results are easy to separate from the sequence they came from.

Engineering decisions need inspectable evidence: upstream tables, residue annotations, structures, confidence scores, logs, and downloadable files.

Annotate, triage, model, and export

Move from antibody sequence or structure inputs to numbered regions, humanness and developability evidence, modeled structures, complexes, and exportable review packets.

Review humanization evidence

Compare humanness and humanization signals while keeping each score and residue-level output tied to its input sequence.

Start humanization review

Model antibody structures

Predict antibody or nanobody structures from sequence, inspect model confidence, and export the generated structure files.

Open ImmuneBuilder

Explore antibody-antigen binding

Route paired chains and antigen structures into complex modeling or docking workflows, then inspect scores and structures together.

Explore docking

Questions & answers

Start antibody engineering in ProteinIQ

MonthlyAnnual (save 20%)

Free

$0

Includes:

  • 100 credits
  • 3 jobs per day
  • 1 concurrent job
  • 1 workflow
  • 1 seat
  • Core tool features
  • Academic license

Lite

$9$7/month

Everything Free, plus:

  • 500 credits / month
  • No daily job limit
  • 2 concurrent jobs
  • 3 workflows
  • Advanced tool settings
  • AI assistant, SVG export, batch runs, and workflows

Plus

$29$23/month

Everything Lite, plus:

  • 2,000 credits / month
  • 5 concurrent jobs
  • 5 workflows

Pro

Best value
$99$79/month

Everything Plus, plus:

  • 8,000 credits / month
  • 10 concurrent jobs
  • 20 workflows
  • Commercial license

Enterprise

Custom

Everything Pro, plus:

  • Custom credit allocation
  • Shared workspace seats and credits
  • Invoice billing, purchase orders, and vendor setup
  • Unlimited workflows
  • Custom workflows, integrations, and security review