{
  "last_checked": "2026-10-29",
  "license": "CC BY 4.0. Credit: ProteinIQ, https://proteiniq.io/guides/approved-radiopharmaceutical-therapies",
  "source": "ClinicalTrials.gov API v2",
  "api_version": {
    "apiVersion": "2.0.5",
    "dataTimestamp": "2026-10-29T09:00:05"
  },
  "queries": [
    "lutetium OR 177Lu OR Lu177 OR \"Lu-177\" OR \"Lu 177\" OR Lutathera OR Pluvicto OR vipivotide",
    "actinium OR 225Ac OR Ac225 OR \"Ac-225\" OR \"FPI-2265\" OR RYZ101",
    "\"lead-212\" OR 212Pb OR Pb212 OR \"Pb-212\" OR AlphaMedix OR DOTAMTATE OR \"VMT-\u03b1-NET\" OR VMT01",
    "terbium OR 161Tb OR \"Tb-161\"",
    "\"copper-67\" OR 67Cu OR \"Cu-67\"",
    "\"iodine-131\" OR 131I OR \"I-131\" OR \"I 131\" OR radioiodine OR \"radioactive iodine\" OR Azedra OR Bexxar OR tositumomab OR Iomab OR apamistamab OR omburtamab",
    "yttrium OR 90Y OR \"Y-90\" OR Y90 OR Zevalin OR ibritumomab",
    "radium OR 223Ra OR \"Ra-223\" OR 224Ra OR \"Ra-224\" OR Xofigo OR Alpharadin",
    "samarium OR 153Sm OR \"Sm-153\" OR Quadramet OR strontium OR 89Sr OR \"Sr-89\" OR Metastron",
    "rhenium OR 188Re OR 186Re OR \"Re-188\" OR \"Re-186\" OR holmium OR 166Ho OR \"Ho-166\"",
    "astatine OR 211At OR \"At-211\" OR bismuth OR 213Bi OR \"Bi-213\" OR thorium OR 227Th OR \"Th-227\"",
    "\"phosphorus-32\" OR 32P OR \"P-32\" OR scandium OR 47Sc OR \"Sc-47\" OR erbium OR 169Er OR \"Er-169\""
  ],
  "filter": "AREA[StudyType]INTERVENTIONAL",
  "candidates_retrieved": 2049,
  "therapeutic_trials": 1041,
  "active_or_recruiting": 362,
  "by_isotope": {
    "Lu-177": 363,
    "I-131": 260,
    "Y-90": 195,
    "Ra-223": 78,
    "Ac-225": 73,
    "Sm-153": 19,
    "Pb-212": 15,
    "At-211": 14,
    "Tb-161": 11,
    "Sr-89": 9,
    "Re-188": 8,
    "Re-186": 6,
    "Ho-166": 6,
    "Cu-67": 4,
    "Ra-224": 3,
    "P-32": 3,
    "Bi-213": 2
  },
  "by_phase": {
    "Phase 2": 333,
    "Phase 1": 299,
    "Phase 1/2": 176,
    "Phase 3": 91,
    "Not applicable": 62,
    "Early phase 1": 55,
    "Phase 4": 15,
    "Phase 2/3": 10
  },
  "excluded_diagnostic_or_screening_purpose": {
    "I-131": 19,
    "Lu-177": 10,
    "Y-90": 3,
    "Ra-223": 1,
    "Pb-212": 1,
    "Cu-67": 1,
    "Ac-225": 1
  },
  "device_only_trials_not_counted": {
    "P-32": 9,
    "Y-90": 165,
    "Ho-166": 15,
    "I-131": 6,
    "Ra-224": 9,
    "Re-188": 2,
    "Ra-223": 1,
    "Lu-177": 1
  },
  "title_only_matches_not_counted": 33,
  "generated": "2026-10-29"
}